Anthrax is the terrorist weapon of choice. Unlike infectious plague and smallpox which can travel across borders and kill unintended targets, anthrax (shown at right) kills only where it is delivered.
Anthrax kills by releasing two toxins into the body, they are called edema toxin and lethal toxin.1 It is not the anthrax itself which is deadly, but these two toxins it produces. If you could neutralize these two toxins, you could live long enough for the antibiotics to work.
To be effective against pulmonary Anthrax, antibiotics must be given before symptoms occur. The toxins that Anthrax produces are so deadly, that by the time the victim is symptomatic, it is too late. The toxins will kill the victim before the antibiotics have time to act. The key to surviving Anthrax after symptoms manifest is to neutralize these two toxins. Destroy the toxins, and you may be able to survive long enough for antibiotics to be effective. Unfortunately, you may not know you have Anthrax until you are already symptomatic, so unless you want to be continuously on antibiotics, you may not be able to keep from getting Anthrax. Even if you were to stay on antibiotics (which has side effects of its own), future Anthrax strains might be antibiotic resistant.
Anthrax toxins turn off the immune system. If you can neutralize the toxins, your own immune system may be able to destroy the Anthrax just like any infection. This is important since 1) you may not have access to antibiotics, and 2) it may be an antibiotic resistant strain.
Edema toxin, one of the two toxins produced by Anthrax inhibits the neutrophils,2 the white blood cells responsible for attacking bacteria. Anthrax is a bacteria. Thus Anthrax is like AIDS, it inhibits the very part of the immune system required to destroy it. Knock out the Edema toxin and your immune system may be able to fight the infection itself.
Lethal toxin, the other toxin produce by Anthrax, stimulates the macrophages (white blood cells) to release tumor necrosis factor a and interleukin-1b, which are partly responsible for sudden death in systemic anthrax.3 Tumor necrosis factor (TNF) is how the body fights cancer (and bacterial toxins). Unfortunately, TNF has the side effects of cachexia (wasting away) and toxic shock. Thus while trying to fight the Anthrax, our body inadvertently creates the very substances (TNF) that cause us to go into shock and die.
The two toxins Anthrax makes, Edema Toxin and Lethal Toxin, both have an Achilles heel that we can take advantage of. They both need certain minerals to work. Let's look at them more closely. Edema toxin has a protein called calmodulin 4 in it. Calmodulin has been called the "gatekeeper molecule" in biochemistry. The mineral calcium is required for this "gate" to operate. Without calcium, Calmodulin cannot work. Without Calmodulin, Edema Toxin may become inactive.* Calmodulin molecule shown at right.
Perhaps the reason that the vast majority of the deaths in the Russian Anthrax exposure were older people is that as we age, calcium builds up inside the cells. It may be that the younger people did not have enough calcium build up inside their cells to allow the calmodulin to work.
Lethal Toxin has a zinc-bearing enzyme in it.5 This enzyme absolutely requires zinc to function. Without zinc, Lethal toxin cannot work.** Metalloenzyme molecule shown at right.
Remove the Zinc and the Lethal toxin cannot operate!
EDTA can remove both zinc and calcium from the bloodstream quickly and safely. EDTA, a synthetic amino acid and food preservative, has been used for the last 50 years to remove lead and other heavy metals from the bloodstream as a treatment for heavy metal poisoning. Luckily for us, EDTA, along with removing the heavy metals, also removes calcium and zinc. There is every reason to believe that EDTA, (shown at right) can remove the calcium and zinc from Edema Toxin and Lethal Toxin as well. In this way, EDTA may act as an anti-toxin / antidote.
EDTA can remove calcium and zinc from the bloodstream and the toxins!
EDTA can be taken 3 ways: orally, intravenously and by suppository.
Make sure that you get Magnesium Di-Potassium EDTA suppositories, not a calcium based EDTA suppository. A calcium based EDTA will not remove calcium and therefore cannot effect Edema toxin. Magnesium Di-Potassium EDTA is the preferred type of EDTA suppository.
The toxins cause nonspecific flu-like symptoms: mild fever, malaise, fatigue, muscle pain, dry cough, and at times a sensation of chest oppression. This phase can last for several days or as little as 24 hours, and can be followed by a period with no symptoms. The second phase develops suddenly with severe shortness of breath, plunging blood pressure and shock. This phase typically lasts less than 24 hours and usually ends in death despite therapy, due to the high number of toxin-producing organisms that have developed (if you haven't neutralized the toxins of course).
* Edema toxin consists of edema factor, which is a calmodulin-dependent adenylate cyclase. Calmodulin upon the binding of Ca2++ undergoes a conformational change needed for its biological activity . EDTA can remove Ca2++ both from the bloodstream and tissues, and may also be able to remove Ca2++ from the calmodulin. Thus removing the Ca2++ makes the calmodulin biologically inactive or less active.6
** Lethal Toxin consists of lethal factor, which is a zinc metalloprotease.
*** Normal dosage is one suppository every two or three days for heavy metal poisoning. One suppository every two hours may irritate the rectum, but the discomfort would certainly be preferable to symptomatic anthrax.
There are a number of things that must be addressed with symptomatic Anthrax. The main issues are in bold with some ideas about what might work to deal with them. In many ways, Anthrax kills the same way a bee sting might kill someone allergic to bee venom. It is not necessarily the toxins which kill, but the body's reaction to the toxins. If you can turn off the reaction, you may live long enough for the antibiotic to work.
None of this material is meant as medical advice. This is for research purposes only.